The most prevalent type of arthritis is osteoarthritis. Its incidence in the United States is estimated to be between 20 and 40 million people.Learn more by visiting  How to Regrow Cartilage

Premature degeneration of articular cartilage, the gristle that covers the ends of long bones, is the underlying pathology. Cartilage is a connective tissue type. It is remarkable in that it gets its nutrition from the synovium, the joint lining. There are no blood vessels or nerves in cartilage.

The pain associated with osteoarthritis is caused by irritation caused by local inflammation. The generation of damaging enzymes, as well as local irritation caused by altered biomechanics, cause these local inflammatory alterations.

Osteoarthritis has traditionally been treated solely on a symptomatic basis. Oral or topical nonsteroidal anti-inflammatory medications, local joint injections of glucocorticoids, or intra-articular injections of viscosupplements are all options (lubricants).

While these methods may temporarily relieve pain, they are also associated with potential adverse effects and do not address the underlying issue of articular cartilage loss.

There was a lot of interest in creating disease-modifying osteoarthritis medications in the 1990s (DMOADS). However, research into these disease-modifying treatments has been unsatisfactory.

Recently, there has been increased interest in using stem cells to aid cartilage regeneration.

However, there have been numerous questions raised by this line of thought. What are the best SCs to use? What inhibits the SCs from escaping from the joints? What can be done to make the SCs more productive? When are they going to cease working? How can you get the SCs to create cartilage in the proper environment? What are the risks of becoming involved? What factors are used to choose the best SCs expert?

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